L-3-Aminoisobutyric acid (CAS# 4249-19-8)

Isingeniso

I-Sb-aminoisobutyric acid(S-β-aminoisobutyric acid) iyi-amino acid enesakhiwo esithile. Kuyi-amino acid engeyona eyemvelo enefomula yamangqamuzana engu-C4H9NO2 kanye nesisindo samangqamuzana esingu-103.12g/mol.

I-Sb-aminoisobutyric acid ingesinye se-stereoisomers ezimbili, futhi ukucushwa kwayo kwe-stereo kuhlala kuyi-L. Kuyimpushana emhlophe ecwebezelayo, encibilika emanzini nasezincibilikisini zotshwala. Inhlanganisela izinzile emoyeni kodwa izwela ukushisa nokukhanya.

I-Sb-aminoisobutyric acid inemisebenzi eminingi ebalulekile yomzimba ku-vivo, okuhlanganisa i-protein metabolism, ukulawulwa kokuzivikela komzimba kanye nomthelela ekusebenzeni kobuchopho. Ingasetshenziswa futhi njenge-chiral charged kanye ne-fatty acid oxidase carrier intracellular.

I-Sb-aminoisobutyric acid isetshenziswa kakhulu emkhakheni wezokwelapha wezidakamizwa zokwenziwa, ukwelashwa okulwa nomdlavuza kanye nocwaningo lwamakhemikhali. Ingasetshenziselwa ukutadisha umsebenzi wamaprotheni nama-enzyme, ukwakheka kwamaprotheni nama-nucleic acid, kanye nokwenza ama-antibiotics, ama-analgesics nezinye izinhlanganisela ze-bioactive.

Izindlela zokulungiselela i-Sb-aminoisobutyric acid ingahlanganiswa noma ikhishwe emithonjeni yemvelo. Enye indlela evamile yokwenziwa iwukuba amination of isovaleraldehyde. Ukukhishwa emithonjeni yemvelo ngokuvamile kuvela kuma-metabolites amagciwane athile noma isikhunta.

Mayelana nolwazi lokuphepha, i-Sb-aminoisobutyric acid ngokuvamile ibhekwa njengephephile uma kuqhathaniswa nokusetshenziswa kwezimboni okuvamile kanye nemisebenzi yaselabhorethri. Nokho, kuseyikhemikhali futhi kufanele kube ngaphansi kwezinqubo zokuphepha ezifanele zaselabhorethri. Lapho echayeke kuyo, kufanele athathe izinyathelo zokuzivikela ezifanele, okuhlanganisa ukugqoka amagilavu, izibuko nezingubo zokuzivikela. Uma kwenzeka ukuthintana ngephutha noma ukumunca, ukunakekelwa kwezempilo kufanele kufunwe ngokushesha.