I-L-Fmoc-Aspartic acid alpha-tert-butyl ester (CAS# 129460-09-9)
I-Fluorenylmethoxycarbonyl-aspartate-l-tert-butyl ester (Fmoc-Asp(tBu)-OH) iyiqembu elivame ukusetshenziswa elivikelayo le-aspartic acid. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukwakhiwa kanye nolwazi lokuphepha:
Imvelo:
-Ifomula yamakhemikhali: C26H27NO6
Isisindo samangqamuzana: 449.49g/mol
-Ukubukeka: I-crystalline emhlophe eqinile
-Indawo yokuncibilika: 205-207°C
Sebenzisa:
- I-Fmoc-Asp(tBu) -OH ivamise ukusetshenziswa ekuhlanganiseni kwe-peptide ekuhlanganiseni kwesigaba esiqinile njengeqembu elivikela i-aspartic acid.
-Ingakhiqiza amaketanga e-peptide ngokwethula izinsalela ze-aspartic acid ngokulandelana kwe-peptide yokwenziwa ngokusebenzisa ukuhlanganiswa kwesigaba esiqinile.
Indlela Yokulungiselela:
- I-Fmoc-Asp(tBu)-OH ingatholakala ngokusabela i-isopropyl acetate noma i-sodium hydroxide nge-Fmoc-Asp(tBu)-OH.
Ulwazi Lokuphepha:
- I-Fmoc-Asp(tBu)-OH isetshenziswa kakhulu embonini nasemalabhorethri, futhi ngokuvamile ibhekwa njengento ephephile uma kuqhathaniswa.
-kodwa usadinga ukunaka ubuthi nokucasuka kwayo.
-Lapho uyiphatha, gqoka izinto zokuzivikela ezifanele, njengamagilavu nezibuko, ukuvimbela ukuthintana nesikhumba noma amehlo.
-Uma ugcina futhi uphatha, kunconywa ukuthi uyigcine endaweni eyomile, epholile, kude nomlilo kanye nama-oxidizing agents.
Sicela uqaphele ukuthi ukuphepha kwamakhemikhali kudinga ukuphathwa ngokuqapha. Ukuhlola kufanele kwenziwe ngokuhambisana neziqondiso zokusebenza eziphephile kanye nokulahlwa kwemfucuza ngokuhambisana nemithethonqubo efanele.
