I-Lacosamide (CAS# 175481-36-4)
Ubungozi Nokuphepha
| Amakhodi Engozi | I-R11 – Ivutha Kakhulu R20/21/22 – Kuyingozi ngokuhogela umoya, ukuthintana nesikhumba futhi uma ukugwinyile. R36 – Ukucasuka emehlweni |
| Incazelo Yokuphepha | S16 – Zigcine kude nemithombo yokuthungela. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. I-S36/37 – Gqoka izingubo zokuzivikela ezifanele namagilavu. |
| Ama-ID e-UN | UN 1648 3 / PGII |
| I-WGK Germany | 2 |
| Ikhodi ye-HS | 2924296000 |
I-Lacosamide (CAS# 175481-36-4) isingeniso
I-Lactamide yikilasi lezinhlanganisela eziphilayo eziqukethe izindandatho ze-lactam. Okulandelayo yisingeniso sezakhiwo, ukusetshenziswa, izindlela zokulungiselela kanye nolwazi lokuphepha lwe-laclamide:
Ikhwalithi:
Izakhiwo ze-laclamide zincike ekwakhekeni kwayo kwamangqamuzana nobukhulu bendandatho. Ngokuvamile, i-lacamide iyikristalu emhlophe eqinile enokuqina okuqinile. Inoncibilika kahle, inyibilika kuzincibilikisi zemvelo njengama-ether nama-ketone, futhi ayincibiliki emanzini.
Sebenzisa:
I-Laccamide inezinhlobonhlobo zezicelo embonini yamakhemikhali. Okubaluleke kakhulu kwalokhu ukusetshenziswa kwayo njengesandulela sezinto ze-polymer. Isibonelo, imicu ye-polyamide (inayiloni) yenziwa nge-polymerizing laclamide. I-laxamide ingasetshenziswa futhi njengesithako esimaphakathi kwizincibilikisi, izinto ezincibilikisayo, nanjengento engavuthiwe yokwakha imicu yokwenziwa, irabha yokwenziwa, imithi kanye nodayi.
Indlela:
Ngokuvamile, ukuhlanganiswa kwe-laxamide kutholakala ngokuyinhloko nge-acid-catalyzed cyclization. Ikakhulukazi, izindlela zokulungiselela ezisetshenziswayo yilezi ezilandelayo:
Indlela ye-pamine: isebenzisa ama-amine ne-asidi chloride noma i-anhydride ukuze isabele ngaphansi kwezimo ezifanele ukukhiqiza i-laxamide.
Izindlela ze-non-classical acid catalytic: Isibonelo, ngemva kokuthi i-medium ku-catalytic reactor ilaphe ngokuphelele, i-ferric chloride kanye ne-acid catalyst ingaguqulelwa ku-laclamide emazingeni okushisa aphansi.
Indlela yokusabela ngomfutho ophezulu: I-Laclamine ihlanganiswa idivayisi ye-imimine kanye ne-NBS endaweni enengcindezi ephezulu.
Ulwazi Lokuphepha:
I-Laxamide iyikhemikhali futhi kufanele igcinwe ngendlela efanele endaweni eyomile, epholile, kude nemithombo yomlilo nama-oxidants.
Ngesikhathi sokusebenza, izimo zokungena komoya ezinhle kufanele zigcinwe futhi kusetshenziswe izinto zokuzivikela ezifanele ezifana namagilavu okuvikela, izihlangu zobuso, nezingubo zamehlo ezivikelayo.
I-Laclamide ingacasula isikhumba namehlo.
Lapho kulahlwa imfucuza, kufanele ilahlwe ngendlela efanele ngokuhambisana nemithetho yendawo.
