I-Metomidate (CAS# 5377-20-8)

Isingeniso

Okulandelayo yisingeniso semvelo, ukusetshenziswa, indlela yokukhiqiza, kanye nolwazi lokuphepha lwe-Metomidate:

Ikhwalithi:

1. Ukubukeka: Uhlobo oluvamile lwe-Metomidate luqinile olumhlophe.

2. Ukunyibilika: Inokuncibilika okuphansi emanzini futhi iyancibilika kuzincibilikisi zemvelo ezifana ne-methanol ne-ethanol.

Sebenzisa:

I-Metomidate ivame ukusetshenziswa njenge-ejenti yokubulala izinzwa yezilwane kanye ne-hypnotic. Kuyi-GABA receptor agonist ekhiqiza umphumela wokuzola nokulutha ngokuthinta izindlela ezithile ohlelweni lwezinzwa olumaphakathi. Emithini yezilwane, ijwayele ukusetshenziselwa i-anesthesia ezinhlanzi, izilwane ezihlala emanzini nasezilwaneni ezihuquzelayo.

Indlela:

Ukulungiswa kwe-Metomidate kuvame ukubandakanya lezi zinyathelo ezilandelayo:

1. I-3-cyanophenol ne-2-methyl-2-propanone zifinyezwa ukuze zenze okuphakathi.

2. Okumaphakathi kusabela nge-formaldehyde ngaphansi kwezimo ze-alkaline ukwenza isandulela se-Metomidate.

3. Ukushisa kanye ne-hydrolysis yesandulela ngaphansi kwezimo ze-alkali ukukhiqiza umkhiqizo wokugcina we-Metomidate.

Umzila othize wokuhlanganisa ungalungiswa ngokuya ngenqubo nezimo ezithile.

Ulwazi Lokuphepha:

1. I-Metomidate iwumuthi obulala izinzwa futhi kufanele isetshenziswe ngokuhambisana nezimiso zokuphepha ezifanele.

3. Ingase ibe nemiphumela ohlelweni lwezinzwa olumaphakathi, ngakho-ke kufanele kucatshangelwe ngokucophelela uma uyisebenzisa ukuze ugweme ukusetshenziswa ngokweqile.

4. I-Metomidate iwubuthi futhi izindlela zokulawula amakhemikhali ezifanele kufanele zilandelwe ngesikhathi sokugcinwa nokuphathwa.