I-N-Carbobenzyloxy-L-proline(CAS# 1148-11-4)
I-Cbz-L-Proline, igama layo eliphelele lingu-L-Proline-9-Butyroyl Ester, iyinhlanganisela yezinto eziphilayo. Okulandelayo yisingeniso sezakhiwo, ukusetshenziswa, izindlela zokulungiselela kanye nolwazi lokuphepha lwe-Cbz-L-proline:
Ikhwalithi:
- Ukubukeka: I-crystalline emhlophe noma i-crystalline powder.
- Ukuncibilika kukasawoti: ukuncibilika kuma-asidi, akuncibiliki emanzini.
Sebenzisa:
- I-Cbz-L-proline ivame ukusetshenziswa njengeqembu elivikelayo ku-organic synthesis ukuvikela amaqembu amino (NH₂) kuma-amino acid.
- Isetshenziswa kakhulu ekuhlanganiseni kwamakhemikhali ama-peptides namaprotheni.
Indlela:
Ukulungiswa kwe-Cbz-L-proline ngokuvamile kwenziwa ngezinyathelo ezilandelayo:
1. I-Proline isabela nge-chloroformate-9-butyl ester ngaphansi kwezimo ze-alkaline ukuze kutholwe i-substrate.
2. I-substrate iphathwa ngaphansi kwezimo ezine-acidic ukuze ikhiqize i-Cbz-L-proline.
Ulwazi Lokuphepha:
- I-Cbz-L-Proline iyikhemikhali futhi kufanele iphathwe ngokucophelela. Qaphela ukuthi ungathintani nesikhumba namehlo, futhi ugweme ukuhogela.
- Gqoka izinto zokuzivikela ezifanele ezifana namagilavu zelabhu nezibuko lapho usetshenziswa.
- Gcina uvalwe ngokuqinile futhi ugweme ukukhanya kwelanga kanye namazinga okushisa aphezulu.
- Ngemuva kokusetshenziswa nokuphatha, landela imithetho yendawo yokulahla amakhemikhali.
