N-Boc-N'-(9-xanthenyl)-L-glutamine (CAS# 55260-24-7)

Isingeniso

I-N(alpha)-boc-N-(9-xanthenyl)-L-glutamine(N(alpha)-boc-N-(9-xanthenyl)-L-glutamine) ingxube yemvelo. Ifomula yayo yamangqamuzana ithi C26H30N2O6 futhi isisindo sayo samangqamuzana ngu-466.52.

Imvelo:

I-N(alpha)-boc-N(delta)-(9-xanthenyl)-L-glutamine iqinile, incibilika kwezinye izincibilikisi eziphilayo njenge-dimethyl sulfoxide ne-methylene chloride. Inhlanganisela inemvelo yekristalu emhlophe kuya kokuphuzi.

Sebenzisa:

I-N(alpha)-boc-N(delta)-(9-xanthenyl)-L-glutamine ivamise ukusetshenziswa ku-organic synthesis, ikakhulukazi ku-peptide synthesis kanye nokuthuthukiswa kwezidakamizwa, njengama-synthetic precursors noma okuphakathi. Ingasetshenziswa njenge-reagent ukwenza kusebenze ama-amino acid avikelwe ukuze kulawulwe ukusebenza kabusha kwawo kanye nokukhetha ngesikhathi sokwakheka kwe-peptide.

Indlela Yokulungiselela:

ukulungiswa kwe-N(alpha)-boc-N(delta)-(9-xanthenyl)-L-glutamine ngokuvamile kuhilela ukusabela okunezinyathelo eziningi, indlela evamile kakhulu iwukusuka ku-N-protected glutamine, ngokusebenzisa uchungechunge lokuvikela kanye ukusabela kokuvikela, futhi ekugcineni nge-9-oxanthenoic acid amino acid activation reaction ukuze uthole umkhiqizo.

Ulwazi Lokuphepha:

ulwazi oluthile lokuphepha mayelana ne-N(alpha)-boc-N(delta)-(9-xanthenyl)-L-glutamine okwamanje alutholakali esidlangalaleni. Kodwa-ke, njengento yamakhemikhali, lapho isetshenziswa, kufanele ihambisane ngokuqinile nezinqubo zokuphepha zaselabhorethri, isebenze ngaphansi kwemibandela yezindawo zokuzivikela, futhi igweme ukuthintana ngqo nesikhumba, amehlo kanye nokuhogela uthuli lwayo. Xhumana nochwepheshe noma ubhekisele eshidini ledatha yezokuphepha elifanele ukuze uthole ukuhlolwa kokuphepha kanye neziqondiso zokusebenza zale nhlanganisela.