N-Cbz-L-Leucine(CAS# 2018-66-8)
Ubungozi Nokuphepha
| Izimpawu Eziyingozi | I-Xn - Iyingozi |
| Amakhodi Engozi | U-R10 – Uyavutha U-R20/22 – Kuyingozi ngokuhogela umoya futhi uma ugwinyiwe. R37/38 – Ukucasula uhlelo lokuphefumula kanye nesikhumba. R40 – Ubufakazi obuncane bomphumela we-carcinogenic R41 – Ingozi yokulimala okubi emehlweni R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. R20/21/22 – Kuyingozi ngokuhogela umoya, ukuthintana nesikhumba futhi uma ukugwinyile. R67 – Izihwamuko zingadala ukozela kanye nesiyezi R63 – Ingozi engaba khona yokulimala enganeni engakazalwa I-R19 – Ingase yenze ama-peroxides aqhumayo |
| Incazelo Yokuphepha | S16 – Zigcine kude nemithombo yokuthungela. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu kanye nokuvikela iso/ubuso. S45 – Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.) S36 – Gqoka izingubo ezifanele zokuzivikela. I-S36/37 – Gqoka izingubo zokuzivikela ezifanele namagilavu. S60 – Le nto kanye nesiqukathi sayo kumele kulahlwe njengemfucuza eyingozi. |
| Ama-ID e-UN | UN 1993 3/PG 3 |
| I-WGK Germany | 3 |
| I-RTECS | OH2921000 |
| Ikhodi ye-HS | 29242990 |
N-Cbz-L-Leucine (CAS# 2018-66-8) isingeniso
I-Cbz-L-leucine, igama eligcwele le-Boc-L-leucine (i-Boc imele iqembu elivikelayo le-dibutoxycarbonyl), iphuma kokunye kwe-amino acid. Okulandelayo yisingeniso semvelo yayo, ukusetshenziswa, izindlela zokukhiqiza kanye nolwazi lokuphepha:
Ikhwalithi:
- Ukubukeka: Okuqinile kwekristalu emhlophe
- I-Soluble: I-Soluble ku-ethanol, i-dimethylformamide (DMF) ne-dichloromethane
Sebenzisa:
- I-CBZ-L-Leucine iyiqembu elivame ukusetshenziswa elivikela i-amino acid elivikela iqembu le-hydroxyl leucine ngesikhathi sokuhlanganiswa kwama-peptides ukuze livinjwe ukuthi lingasabeli namanye ama-reactants. Ku-peptide synthesis lapho izinsalela eziningi ze-leucine zidinga ukwethulwa, i-Cbz-L-leucine ingasetshenziswa ukuvikela iqembu le-hydroxyl leucine ngezinqubo zokuhlanganiswa ezilandelayo.
- I-Leucine iyi-amino acid ebalulekile edlala indima ebalulekile ekwakhiweni kwamaprotheni kanye nokusebenza.
Indlela:
- Ukulungiswa kwe-Cbz-L-leucine ngokuvamile kutholakala ngokusabela kwe-leucine nge-Boc-OSu (Boc—N-nitrocarbonyl-L-leucine). Ekuphenduleni, i-Boc-OSu isebenza njengomethuli weqembu elivikelayo futhi ibhekana nokusabela kwe-esterification ne-leucine ukuze ikhiqize i-Cbz-L-leucine.
Ulwazi Lokuphepha:
- I-Cbz-L-leucine iyikhemikhali futhi kufanele igcinwe kahle kude nokuvutha kanye nama-oxidants.
- Ngesikhathi sokusebenzisa, gwema ukuhogela uthuli lwayo noma ukuthintana nesikhumba namehlo.
- Landela izinqubo zokuphepha ezifanele lapho uphatha futhi ulondoloza, futhi ugqoke izinto zokuzivikela ezifanele ezifana namagilavu elebhu nokuvikela amehlo.
