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umkhiqizo

I-N-Fmoc-N-4-methoxy-2,3,6-trimethylbenzenesulfonyl-L-arginine CAS 98930-01-9

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C31H36N4O7S
I-Molar Mass 608.71
Ukuminyana 1.35±0.1 g/cm3(Kubikezelwe)
Ukubukeka Impushana
Umbala Emhlophe
pKa 3.83±0.21(Okubikezelwe)
Isimo Sesitoreji Ivalwe endaweni eyomile, Gcina efrijini, ngaphansi kuka -20°C
Kuyazwela Kuyazwela Umswakama
I-Refractive Index 1.634

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ubungozi Nokuphepha

Amakhodi Engozi R45 – Ingabangela umdlavuza
R46 - Ingabangela ukulimala kofuzo
R20/21/22 – Kuyingozi ngokuhogela umoya, ukuthintana nesikhumba futhi uma ukugwinyile.
R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba.
Incazelo Yokuphepha S53 – Gwema ukuchayeka – thola imiyalelo ekhethekile ngaphambi kokuyisebenzisa.
S22 - Ungaphefumuli uthuli.
S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu ​​kanye nokuvikela iso/ubuso.
S45 – Uma kwenzeka ingozi noma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula noma nini lapho kunokwenzeka.)
I-WGK Germany 3
AMAKHODI E-FLUKA BRAND F 10-21
Ikhodi ye-HS 29350090
I-Hazard Class I-IRRITANT

Ulwazi Lwereferensi

Sebenzisa I-N-Fmoc-N '-(4-methoxy-2, 3, 6-trimethylbenzenesulfonyl) I-L-arginine iphuma ku-amino acid futhi ilusizo njengesisebenzi esisebenza nge-Biochemical.

 

Isingeniso
I-N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl) -L-arginine iphuma e-arginine. Nalu olunye ulwazi mayelana nezakhiwo zayo, ukusetshenziswa, izindlela zokukhiqiza, nokuphepha:

Ikhwalithi:
3. Ukubukeka: okuqinile okucwebezelayo okumhlophe
5. Ukunyibilika: kuncibilika kuma-organic solvents afana ne-dimethyl sulfoxide (DMSO), i-dimethylformamide (DMF), njll.

Sebenzisa:
I-N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine isetshenziswa kakhulu njengeqembu elivikelayo ku-solid phase peptide synthesis (SPPS) ukuvimbela i-arginine ukuthi ingaphatheki kabi namanye ama-reactants, futhi futhi isetshenziselwe ukwenza ama-peptides namaprotheni.

Indlela:
Ukulungiswa kwe-N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl) -L-arginine ngokuvamile kwenziwa ngokuhlanganisa amakhemikhali. Izinyathelo eziyinhloko zihlanganisa ukuhlanganiswa kwe-N-Fmoc-arginine, i-benzoxazolesulfonyl chloride reagent kanye nokusabela kwe-methanol ukuze kutholwe i-N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl) -L-arginine.

Ulwazi Lokuphepha:
1. I-N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine iyikhemikhali futhi kufanele ilandelwe ngokuhambisana nezinqubo zokuphepha zaselabhorethri;
2. Gqoka izibuko zokuzivikela namagilavu ​​lapho usebenzisa ukugwema ukuthintana ngqo nokuhogela;
3. Uma kwenzeka uthinta isikhumba noma amehlo ngengozi, geza ngokushesha ngamanzi amaningi futhi ufune ukwelashwa;
4. Lapho uyigcina, kufanele ivalwe futhi igcinwe kude nomlilo kanye ne-oxidant.


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