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I-N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6) Isithombe Esifakiwe
  • I-N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6) 1

I-N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6)

Isakhiwo Samakhemikhali:

I-Molecular Formula I-C40H33N3O4
I-Molar Mass 619.71
Ukuminyana 1.24±0.1 g/cm3(Kubikezelwe)
I-Melting Point 150-155°C(lit.)
I-Boling Point 811.7±65.0 °C(Kubikezelwe)
Ukuzungezisa Okuthile(α) +86.0 °(D/25)(c=5%inCHCl3)
I-Flash Point 444.7°C
Ukuncibilika kwamanzi Incibilika kancane emanzini.
I-Vapor Presure 7.59E-28mmHg ku-25°C
Ukubukeka Ilensi emhlophe
Umbala Okumhlophe kuya kokumhlophe
I-BRN 5204720
pKa 3.06±0.10(Kubikezelwe)
Isimo Sesitoreji 2-8°C

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Sethula i-N-Fmoc-N'-trityl-L-histidine (I-CAS# 109425-51-6), ibhlokhi yokwakha eyi-premium yokuhlanganiswa kwe-peptide eklanyelwe ukuphakamisa amaphrojekthi akho ocwaningo nentuthuko. Le nhlanganisela ehlanzekile iyithuluzi elibalulekile labosokhemisi kanye nezazi zamakhemikhali ezinto eziphilayo abafuna ukwakha ama-peptide ayinkimbinkimbi ngokunemba nokusebenza kahle.

I-N-Fmoc-N'-trityl-L-histidine iwuhlobo oluvikelekile lwe-amino acid histidine, ehlanganisa kokubili i-Fmoc (9-fluorenylmethoxycarbonyl) namaqembu okuvikela e-trityl. Lawa maqembu avikelayo abalulekile ekuqinisekiseni ukuzinza kanye nokusebenza kabusha kwe-amino acid phakathi nenqubo yokuhlanganisa. Iqembu le-Fmoc livumela ukuvikeleka okulula ngaphansi kwezimo eziyisisekelo ezithambile, kuyilapho iqembu le-trityl linikeza ukuvikeleka okwengeziwe ekuphenduleni okungafunwa ohlangothini, okwenza le nhlanganisela ifaneleke ku-solid-phase peptide synthesis (SPPS).

Ngefomula yamangqamuzana engu-C30H31N3O2 kanye nesisindo sengqamuzana esingu-469.59 g/mol, i-N-Fmoc-N'-trityl-L-histidine ibonisa ukuncibilika okuhle kakhulu kuzinyibilikisi ezivamile zezinto eziphilayo, okwenza kube lula ukufakwa kwayo kumaphrothokholi ahlukahlukene okwenziwa. Isakhiwo sawo esiyingqayizivele asigcini nje ngokuthuthukisa ukuzinza kwama-peptide avelayo kodwa futhi sinomthelela emsebenzini wawo wezinto eziphilayo, okuwenza abe yimpahla ebalulekile ekutholakaleni nasekuthuthukisweni kwezidakamizwa.

Kungakhathaliseki ukuthi usebenza ngama-peptide okwelapha, ucwaningo kubhayoloji yamangqamuzana, noma uhlola izindlela ezintsha ku-biochemistry, i-N-Fmoc-N'-trityl-L-histidine iyisinqumo esifanele sezidingo zakho zokuhlanganiswa. Umkhiqizo wethu ukhiqizwa ngaphansi kwezinyathelo eziqinile zokulawula ikhwalithi ukuze kuqinisekiswe izinga eliphezulu lokuhlanzeka nokungaguquguquki, okukuvumela ukuba ugxile ocwaningweni lwakho ngokuzethemba.

Vula amandla amaphrojekthi akho e-peptide synthesis nge-N-Fmoc-N'-trityl-L-histidine. Izwa umehluko ongenziwa ama-reagents ekhwalithi ephezulu elabhorethri yakho namuhla!

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