I-N-(tert-Butoxycarbonyl)glycylglycine (CAS# 31972-52-8)
| Amakhodi Engozi | 43 - Kungabangela ukuzwela ngokuthinta isikhumba |
| Incazelo Yokuphepha | I-S24/25 - Gwema ukuthintana nesikhumba namehlo. I-S36/37 – Gqoka izingubo zokuzivikela ezifanele namagilavu. |
| I-Hazard Class | I-IRRITANT |
Isingeniso
I-Boc-Gly-Gly-OH, eyaziwa ngokuthi i-Boc-Gly-Gly-OH(N-tert-butyloxycarbonyl-glycyl-glycine, i-Boc-Gly-Gly-OH ngamafuphi), iyikhemikhali. Okulandelayo yincazelo yemvelo yayo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha:
1. Imvelo:
I-Boc-Gly-Gly-OH iqinile okumhlophe kuya kokumhlophe okunephoyinti elincibilikayo eliphezulu kanye nokuncibilika okuphansi. Iyazinzile ekamelweni lokushisa, kodwa ingase yonakalise ngaphansi kwezinga lokushisa eliphezulu, ilanga eliqondile noma indawo enomswakama.
2. Sebenzisa:
I-Boc-Gly-Gly-OH iyiqembu elivame ukusetshenziswa elivikela ama-amino acid. Isetshenziselwa ukuvikela iqembu le-amino le-glycylglycine ekuhlanganiseni kwamakhemikhali ukugwema ukusabela kwayo ohlangothini ekuphenduleni kwamakhemikhali. Ngesikhathi sokuhlanganiswa kwe-polypeptide noma amaprotheni, i-Boc-Gly-Gly-OH ingase yengezwe njengeqembu elivikelayo bese isuswa ngaphansi kwezimo ezifanele ukuze kuvunyelwe uchungechunge lwe-polypeptide ukuba lunwetshwe.
3. Indlela yokulungiselela:
Ukulungiswa kwe-Boc-Gly-Gly-OH ngokuvamile kwenziwa ngezindlela ze-organic synthesis. Enye indlela evamile yokulungisa iwukusabela amaqembu amabili e-hydroxyl e-glycine ngokuhlukana ne-Boc-anhydride (tert-butyloxycarbonyl anhydride) ukuze akhe i-Boc-Gly-Gly-OH. Izimo zokusabela zidinga ukulawulwa ngesikhathi sokulungiselela ukuqinisekisa isivuno nokuhlanzeka.
4. Ulwazi Lokuphepha:
I-Boc-Gly-Gly-OH iphephile uma kuqhathaniswa ngaphansi kwezimo ezivamile zaselabhorethri, kodwa lezi zindaba ezilandelayo zisadinga ukunakwa:
-Le nhlanganisela ingase ibangele ukucasuka esikhumbeni, amehlo kanye nendlela yokuphefumula, ngakho-ke sebenzisa izinyathelo zokuzivikela ezidingekayo njengamagilavu aselabhorethri kanye nezibuko lapho ziveziwe.
-Gwema ukuthintana nama-oxidants noma izinto ezivuthayo ngesikhathi sokusetshenziswa noma ukugcinwa ukuze ugweme izimo eziyingozi njengomlilo noma ukuqhuma.
-Ukuphathwa ngendlela efanele kanye nokulahlwa kwezinhlanganisela ezisele kanye nemfucuza elabhorethri, ngokulandela imikhuba nemithetho ephephile yamanje.
