I-Nalpha-Fmoc-Ndelta-trityl-L-glutamine (CAS# 132327-80-1)
Ubungozi Nokuphepha
| Izimpawu Eziyingozi | Xi - Irritant |
| Amakhodi Engozi | R36/37/38 – Ukucasula amehlo, uhlelo lokuphefumula kanye nesikhumba. R53 – Ingabangela imiphumela emibi yesikhathi eside endaweni yasemanzini R43 - Ingabangela ukuzwela ngokuthinta isikhumba |
| Incazelo Yokuphepha | S22 - Ungaphefumuli uthuli. I-S24/25 - Gwema ukuthintana nesikhumba namehlo. S26 – Uma uthintana namehlo, geza ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha. I-S61 - Gwema ukudedelwa endaweni. Bheka imiyalelo ekhethekile / amaphepha edatha okuphepha. S37 – Gqoka amagilavu afanelekile. S24 – Gwema ukuthintana nesikhumba. |
| I-WGK Germany | 3 |
| AMAKHODI E-FLUKA BRAND F | 10-21 |
| Ikhodi ye-HS | 2924 29 70 |
132327-80-1 - Isingeniso
Le nhlanganisela iqinile njengekristalu emhlophe, ayinaphunga. Inephuzu lokuncibilika elingaba ngu-178-180°C futhi liyancibilika kuzincibilikisi zemvelo ezifana ne-dimethylsulfoxide (DMSO) ne-dimethylformamide (DMF), kodwa ayincibiliki emanzini.
Sebenzisa:
I-FMOC-γ-trityl-L-Glu-OH ivame ukusetshenziswa emkhakheni we-peptide synthesis ekuhlanganiseni kwamakhemikhali. Ingasetshenziswa njengeqembu elivikelayo ukuvikela insalela ye-glutamic acid ochungechungeni lwe-peptide, ngaleyo ndlela ilawule ukuhlangana nokuguqulwa kweketango le-peptide.
Indlela Yokulungiselela:
Ukulungiswa kwe-FMOC-γ-trityl-L-Glu-OH kuvame ukutholwa ngokuhlanganiswa kwamakhemikhali. Kafushane, ingatholwa ngokusabela kwe-condensation ye-tritylglycine nge-fluorenecarboxylic acid.
Ulwazi Lokuphepha:
I-FMOC-γ-trityl-L-Glu-OH ayinabo ubuthi obusobala ngaphansi kwezimo ezijwayelekile. Kodwa-ke, njengamanye ama-reagents amakhemikhali, sebenzisa futhi uphathe ngokuhambisana nezinqubo zokuphepha ezifanele zaselabhorethri, gwema ukuthintana ngqo nesikhumba namehlo, futhi uqinisekise ukuthi ziphathwa endaweni enomoya omuhle.
