(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER(CAS# 91229-91-3)
Isingeniso
I-di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate iyinhlanganisela efomula yayo yamakhemikhali ithi C14H23NO6. Okulandelayo incazelo yezakhiwo, ukusetshenziswa, ukulungiswa kanye nolwazi lokuphepha kwenhlanganisela:
Imvelo:
-Ukubukeka: i-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate iyi-crystalline eqinile engenambala ukuya emhlophe.
-I-Solubility: Incibilika kuma-solvents ephilayo njenge-ethanol, i-methanol ne-dimethyl sulfoxide.
-Indawo yokuncibilika: Inhlanganisela iyancibilika cishe ku-104-105°C.
Sebenzisa:
I-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate iwukuphuma okuvame ukusetshenziswa kwe-amino acid, evamise ukusetshenziswa njenge-reagent ekuhlanganiseni kwe-organic. Ingasetshenziselwa ukuhlanganiswa kwezinto eziphilayo ezisebenzayo, njengezidakamizwa nezinto ze-polymer.
Indlela:
Ukulungiswa kwe-di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate ngokuvamile kwenziwa ngalezi zinyathelo ezilandelayo:
1. Chaza i-pyroglutamic acid tert-butyl ester ku-dimethyl sulfoxide eyomile.
2. Inani elifanele le-N,N'-dihydroxyethyl isopropanamide lengeziwe futhi ingxube yokusabela yapholiswa yaba ngaphansi kuka-0°C.
3. Engeza i-di-tert-butyl carbonate kancane ngenkathi ugcina izinga lokushisa lengxube lingaphansi kuka-0°C.
4. Ngemva kokuqedwa kokusabela, ingxube yokusabela yengezwe emanzini ukuze kukhiqizwe imvula eqinile ye-di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate.
5. Umkhiqizo wokugcina utholwe ngezinyathelo ze-crystallization, filtration kanye nokomisa.
Ulwazi Lokuphepha:
I-di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate kufanele isetshenziswe futhi isingathwe ngokuhambisana nezinqubo eziphephile ukugwema ukuchayeka esikhumbeni, emehlweni kanye nokuhogela. Ngaphezu kwalokho, kufanele igcinwe endaweni eyomile, epholile futhi kude nomlilo nama-oxidants. Ukuze uthole ulwazi oluthile lokuphepha, bheka ku-Chemical Safety Data Sheet (MSDS) noma ulwazi olufanele olunikezwa umphakeli.
